UNAMBIGUOUS CHARACTERIZATION OF P-CRESYL SULFATE, A PROTEIN-BOUND UREMIC TOXIN, AS BIOMARKER OF HEART AND KIDNEY DISEASE

Unambiguous Characterization of p-Cresyl Sulfate, a Protein-Bound Uremic Toxin, as Biomarker of Heart and Kidney Disease

p-Cresyl sulfate is one of the bound uremic toxins whose level increases in the sera of patients with the severity of chronic jolly rancher filled gummies kidney disease and is therefore used as a standard for clinical investigations.Our first attempts to obtain p-cresyl sulfate led exclusively to the product of sulfonation of the aromatic ring ins

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An Improved A-Star Ship Path-Planning Algorithm Considering Current, Water Depth, and Traffic Separation Rules

The influence of the maritime environment such as water currents, water depth, and traffic separation rules should be considered when conducting ship path planning.Additionally, the maneuverability constraints of the ship play a crucial role in navigation.Addressing the limitations of the traditional A-star algorithm in ship path planning, this pap

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